Materials and Mechanical Systems, Bioengineering and Bio-mechanics
In 2006, Kosmrlj obtained Diploma (B. Sc.) in Mathematical Physics from the University of Ljubljana, Slovenia. He then moved to Massachusetts Institute of Technology for his graduate studies in physics, where he was coadvised by Arup Chakraborty and Mehran Kardar. For PhD thesis Kosmrlj studied the development of immune system and its response to infecting microorganisms. After receiving PhD in 2011, Kosmrlj became postdoc with David Nelson at Harvard University, where he worked on mechanics of thin membranes and metamaterials.
In 2015 Kosmrlj became assistant professor at Princeton University, where he continues theoretical and computational research of complex systems ranging from materials science to the physics of living systems. Current research includes the design and mechanics of metamaterials, where geometrical shape of structures gives rise to unusual material properties. This includes the role of geometry and topology on the mechanics of structures both at the macro-scale and at the micro-scale, where effects of thermal fluctuations and disorder could be important if one wants to design flexible electronics, sensitive force sensors or micro-actuators. Current research also includes studies of protein aggregates, which have been implicated in a vide variety of diseases, such as Alzheimer’s and Parkinson’s, and are also one limiting factor for drugs that are used for regulating diabetes.
A. Kosmrlj, P. Cordsen, A. Kyrsting, D. E. Otzen, L. B. Oddershede, and M. H. Jensen, “A monomer-trimer model supports intermittent glucagon fibril growth”, Scientific Reports 5, 9005 (2015)
S. H. Kang, S. Shan, A. Kosmrlj, W. L. Noorduin, S. Shian, J. C. Weaver, D. R. Clarke, and K. Bertoldi, “Complex ordered patterns in mechanical instability induced geometrically frustrated triangular cellular structures”, Physical Review Letters 112, 098701 (2014)
A. Kosmrlj, and D. R. Nelson, “Thermal excitations of warped membranes”, Physical Review E 89, 022126 (2014)
A. Kosmrlj and D. R. Nelson, “Mechanical properties of warped membranes”, Physical Review E 88, 012136 (2013)
A. Kosmrlj, M. Kardar, and A. K. Chakraborty, “Statistical Physics of T-Cell Development and Pathogen Specificity”, Annual Review of Condensed Matter Physics 4, 339 (2013)